論文名 | The Safety and Efficacy of Weekly Paclitaxel Administration for Anaplastic Thyroid Cancer Patients : A Nationwide Prospective Study |
著者名 | Onoda, Naoyoshi / Sugino, Kiminori / Higashiyama, Takuya / Kammori, Makoto / Toda, Kazuhisa / Ito, Ken-ichi / Yoshida, Akira / Suganuma, Nobuyasu / Nakashima, Noriaki / Suzuki, Shinichi / Tsukahara, Kiyoaki / Noguchi, Hitoshi / Koizumi, Masanori / Nemoto, Toshimitsu / Hara, Hisato / Miyauchi, Akira / Sugitani, Iwao |
著者名(別言語) | 小野田, 尚佳 / 杉野, 公則 / 東山, 卓也 / 神森, 眞 / 戸田, 和寿 / 伊藤, 研一 / 吉田, 明 / 菅沼, 伸康 / 中島, 範昭 / 鈴木, 眞一 / 塚原, 清彰 / 野口, 仁志 / 小泉, 雅典 / 根本, 俊光 / 原, 尚人 / 宮内, 昭 / 杉谷, 巌 |
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抄録・内容(英) | Background: Anaplastic thyroid cancer (ATC) is a rare and extremely aggressive malignancy, with a median survival of less than 6 months due to rapid progression and resistance to multimodal therapies. Effective treatment strategies have not been identified. A prospective clinical study was performed to objectively evaluate outcomes of treatment with paclitaxel. / Methods: An investigator-initiated, multicenter, nonrandomized, open-label, single-arm study to evaluate the feasibility and efficacy of weekly paclitaxel (80 mg/m2) administration for patients with pathologically confirmed ATC was conducted in a nationwide organization.... |
備考 | This work was supported in part by a grant-in-aid for scientific research from the Japan Society for the Promotion of Science (JSPS KAKENHI #25461992) to N.O., a grant-inaid for strategic research from Osaka City University (Novel Priority Research B) to N.O., and a study grant from the nonprofit organization TODoc Network. |
言語 | eng |
ページ開始 | 1293 |
ページ終了 | 1299 |
著者版フラグ | author |
著者所属(英) | Anaplastic Thyroid Carcinoma Research Consortium of Japan, Osaka City University / Anaplastic Thyroid Carcinoma Research Consortium of Japan, Ito Hospital / Anaplastic Thyroid Carcinoma Research Consortium of Japan, Kuma Hospital / Anaplastic Thyroid Carcinoma Research Consortium of Japan, Kanaji Thyroid Hospital / Cancer Institute Hospital / Anaplastic Thyroid Carcinoma Research Consortium of Japan, Shinshu University / Anaplastic Thyroid Carcinoma Research Consortium of Japan, Kanagawa Cancer Center / Yokohama City University / Tohoku University / Anaplastic Thyroid Carcinoma Research Consortium of Japan, Fukushima Medical University School of Medicine / Tokyo Medical University / Noguchi Thyroid Clinic and Hospital Foundation / Mito Medical Center / Japanese Red Cross Narita Hospital / Anaplastic Thyroid Carcinoma Research Consortium of Japan, Tsukuba University / Anaplastic Thyroid Carcinoma Research Consortium of Japan, Kuma Hospital / Anaplastic Thyroid Carcinoma Research Consortium of Japan, Cancer Institute Hospital, Nippon Medical School |
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刊行年月 | 2016-09-01 |
出版社 | Mary Ann Liebert, Inc. |
ISSN | 1557-9077 |
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資料種別(英語) | Journal Article |
DOI | https://doi.org/10.1089/thy.2016.0072 |
権利 | © Mary Ann Liebert, Inc. The following article has been accepted by Thyroid. Final publication is available from Mary Ann Liebert, Inc., publishers https://doi.org/10.1089/thy.2016.0072 |
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