論文名 | Serum Myostatin Level in COPD Patients with and without Sarcopenia : Application for Biomarker of Sarcopenia Diagnosis |
著者名 | Yoshida, Shinya / Asai, Kazuhisa / Ijiri, Naoki / Kyomoto, Yohkoh / Kawamoto, Tamaki / Okamoto, Atsuko / Yamada, Kazuhiro / Watanabe, Tetsuya / Tochino, Yoshihiro / Kawaguchi, Tomoya |
著者名(別言語) | 吉田, 真也 / 浅井, 一久 / 井尻, 尚樹 / 京本, 陽行 / 川本, 珠貴 / 岡本, 敦子 / 山田, 一宏 / 渡辺, 徹也 / 栩野, 吉弘 / 川口, 知哉 |
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抄録・内容(英) | Background : Chronic obstructive pulmonary disease (COPD) has significant extrapulmonary effects including weight loss, nutritional abnormalities, and skeletal muscle dysfunction. Sarcopenia is one of several comorbidities experienced by COPD patients, which may negatively affect quality of life and increase mortality. Previous studies have reported that exercise may reduce the severity of sarcopenia; however, the mechanism is only partially understood. We hypothesized that levels of irisin and myostatin, one of the myokines, are correlated with sarcopenia in COPD patients. / Methods : A total of 39 male COPD patients were enrolled, in addition to 30 male never-smokers as a control group. Pulmonary function testing was performed on all participants, while body-composition analysis was performed on the COPD patients to measure muscle mass and diagnose sarcopenia.... |
言語 | eng |
ページ開始 | 1 |
ページ終了 | 8 |
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キーワード(英) | |
著者版フラグ | publisher |
著者所属(英) | Osaka City University / Osaka City University / Osaka City University / Osaka City University / Osaka City University / Osaka City University / Osaka City University / Osaka City University / Osaka City University / Osaka City University |
2人目の著者情報 : KAKEN | |
2人目の著者情報 : その他 | |
9人目の著者情報 : KAKEN | |
9人目の著者情報 : その他 | |
10人目の著者情報 : KAKEN | |
10人目の著者情報 : その他 | |
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刊行年月 | 2019-06 |
出版社 | OSAKA CITY MEDICAL ASSOCIATION |
ISSN | 0030-6096 |
雑誌書誌ID(NII) | AA00765896 |
大阪市大OPACへのリンク | SB00009780 |
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資料種別(英語) | Journal Article |
権利 | © 2019 Osaka City Medical Association. |